MSH|^~\&|PTH|SMH|||201911281318||ORU^R01|4116631|D|2.3|||AL|NE
PID|1||SM00041940|LM4541|TEST^ADM^MATILDA||19820507|F||||||||||SM001657/18|9876479911
PV1|1|O
OBR|1|22044|00016632^19RS-1^PTH^19RS-1^22044||||201902041000||||||MFM|201902051108|S^SURGICAL SPECIMEN^SURGICAL|||||19RS-1||201911281318|||SOUT
OBX|1|TX|Pathology Lab: Royal Columbian Hospital
OBX|2|TX|Phone: (604)520-4352 Fax: (604)520-4409
OBX|3|TX| 
OBX|4|TX|Specimen Number: 19RS-1
OBX|5|TX| 
OBX|6|TX| 
OBX|7|TX|ADDENDUM
OBX|8|TX| 
OBX|9|TX|testing
OBX|10|TX| 
OBX|11|TX|                                                    ____________________________________
OBX|12|TX|                                                    Eileen Szeto
OBX|13|TX|                                                    Electronically signed: 28/Nov/2019
OBX|14|TX| 
OBX|15|TX| 
OBX|16|TX|DIAGNOSES
OBX|17|TX|TESTING BIZTALK 2013
OBX|18|TX| 
OBX|19|TX|SYNOPTIC REPORT
OBX|20|TX|--------  Anus - Abdominoperineal Resection, 1  --------
OBX|21|TX| 
OBX|22|TX|SPECIMEN COMMENT
OBX|23|TX|  Pertains To:                         test
OBX|24|TX| 
OBX|25|TX|SPECIMEN
OBX|26|TX|  Procedure:                           Abdominoperineal resection
OBX|27|TX| 
OBX|28|TX|TUMOUR
OBX|29|TX|  Tumour Site:                         Perianal region
OBX|30|TX|  Tumour Size:                         4 x 3 Centimeters (cm)
OBX|31|TX|  Histologic Type:                     Adenocarcinoma
OBX|32|TX|  Histologic Grade:                    G3: Poorly differentiated
OBX|33|TX|  Tumour Extension:                    Tumour directly invades adjacent structures
OBX|34|TX|                                       - test
OBX|35|TX| 
OBX|36|TX|MARGINS
OBX|37|TX|                                       All margins are negtive for invasive
OBX|38|TX|                                       carcinoma and high-grade intraepithelial
OBX|39|TX|                                       neoplasia
OBX|40|TX|  Margins Examined:                    Proximal
OBX|41|TX| 
OBX|42|TX|LYMPH NODES, REGIONAL
OBX|43|TX|                                       No lymph nodes present
OBX|44|TX| 
OBX|45|TX|TREATMENT EFFECT
OBX|46|TX|                                       No known presurgical therapy
OBX|47|TX| 
OBX|48|TX|PATHOLOGIC STAGE
OBX|49|TX|                                       pT4 pNX
OBX|50|TX| 
OBX|51|TX|ANCILLARY STUDIES
OBX|52|TX|  Best Tumour Block(s):                test
OBX|53|TX| 
OBX|54|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|55|TX|---------- End of Synoptic Report ----------
OBX|56|TX|--------  Anus - Abdominoperineal Resection, 2  --------
OBX|57|TX| 
OBX|58|TX|SPECIMEN COMMENT
OBX|59|TX|  Pertains To:                         TESTING V.7.0.0.5
OBX|60|TX| 
OBX|61|TX|SPECIMEN
OBX|62|TX|  Procedure:                           Abdominoperineal resection
OBX|63|TX| 
OBX|64|TX|TUMOUR
OBX|65|TX|  Tumour Site:                         Perianal region
OBX|66|TX|  Tumour Size:                         5.0 Centimeters (cm)
OBX|67|TX|  Histologic Type:                     Adenocarcinoma
OBX|68|TX|  Histologic Grade:                    G3: Poorly differentiated
OBX|69|TX|  Tumour Extension:                    Tumour directly invades adjacent structures
OBX|70|TX|                                       - test test test
OBX|71|TX| 
OBX|72|TX|MARGINS
OBX|73|TX|                                       All margins are negative for invasive
OBX|74|TX|                                       carcinoma and high-grade intraepithelial
OBX|75|TX|                                       neoplasia
OBX|76|TX|  Margins Examined:                    Distal
OBX|77|TX| 
OBX|78|TX|LYMPH NODES, REGIONAL
OBX|79|TX|                                       No lymph nodes present
OBX|80|TX| 
OBX|81|TX|TREATMENT EFFECT
OBX|82|TX|                                       Extensive residual cancer with no evident
OBX|83|TX|                                       tumour regression (poor or no response,
OBX|84|TX|                                       score 3)
OBX|85|TX| 
OBX|86|TX|PATHOLOGIC STAGE
OBX|87|TX|                                       ypT4 pNX
OBX|88|TX| 
OBX|89|TX|ANCILLARY STUDIES
OBX|90|TX|  Best Tumour Block(s):                test
OBX|91|TX| 
OBX|92|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|93|TX|---------- End of Synoptic Report ----------
OBX|94|TX|--------  Breast Invasive Carcinoma, 3  --------
OBX|95|TX| 
OBX|96|TX|SPECIMEN COMMENT
OBX|97|TX|  Pertains To:                         testing v.7.0.0.27
OBX|98|TX| 
OBX|99|TX|SPECIMEN
OBX|100|TX|                                       Skin, Nipple, and Breast; Total mastectomy;
OBX|101|TX|                                       Left
OBX|102|TX| 
OBX|103|TX|TUMOUR
OBX|104|TX|  Invasive Carcinoma:                  Present
OBX|105|TX|    Histologic Type:                   Invasive carcinoma of no special type
OBX|106|TX|                                       (ductal, not otherwise specified)
OBX|107|TX|    Histologic Grade (Nottingham
OBX|108|TX|    Histologic Score)
OBX|109|TX|      Glandular (Acinar) / Tubular
OBX|110|TX|      Differentiation:                 Score 3
OBX|111|TX|      Nuclear Pleomorphism:            Score 3
OBX|112|TX|      Mitotic Rate:                    Score 2
OBX|113|TX|      Overall Nottingham Score:        Grade 3
OBX|114|TX|    Tumour Size:                       3 Millimeters (mm)
OBX|115|TX|    Tumour Focality:                   Single focus of invasive carcinoma
OBX|116|TX|    Lymphovascular Invasion:           Present
OBX|117|TX|    Skin Invasion:                     Skin is uninvolved
OBX|118|TX|    Skin Satellite Foci:               Satellite foci not identified
OBX|119|TX|    Nipple DCIS:                       DCIS does not involve the nipple epidermis
OBX|120|TX|  In Situ Component:                   Not identified
OBX|121|TX| 
OBX|122|TX|MARGINS
OBX|123|TX|  Invasive Carcinoma Margins:          Negative for invasive carcinoma
OBX|124|TX|    Distance from Closest Margin:      Greater than: 4 Millimeters (mm)
OBX|125|TX|    Closest Margin:                    Medial
OBX|126|TX|  DCIS Margins:                        No DCIS present in specimen
OBX|127|TX| 
OBX|128|TX|LYMPH NODES, REGIONAL
OBX|129|TX|                                       No lymph nodes present
OBX|130|TX| 
OBX|131|TX|TREATMENT EFFECT
OBX|132|TX|                                       Treatment information not provided
OBX|133|TX| 
OBX|134|TX|PATHOLOGIC STAGE
OBX|135|TX|                                       pT1a pNX
OBX|136|TX| 
OBX|137|TX|ANCILLARY STUDIES
OBX|138|TX|  Best Tumour Block(s):                test
OBX|139|TX|  Block Tested:                        test
OBX|140|TX|  Results
OBX|141|TX|    ER:                                Negative (Intensity: Negative, 0%), Allred
OBX|142|TX|                                       Score: 0/8
OBX|143|TX|  Controls
OBX|144|TX|    ER Internal Positive Control:      Present
OBX|145|TX| 
OBX|146|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|147|TX|---------- End of Synoptic Report ----------
OBX|148|TX|--------  Breast Invasive Carcinoma, 4  --------
OBX|149|TX| 
OBX|150|TX|SPECIMEN COMMENT
OBX|151|TX|  Pertains To:                         testing v.7.0.0.28
OBX|152|TX| 
OBX|153|TX|SPECIMEN
OBX|154|TX|                                       Breast; Total mastectomy; Left
OBX|155|TX| 
OBX|156|TX|TUMOUR
OBX|157|TX|  Invasive Carcinoma:                  Present
OBX|158|TX|    Histologic Type:                   Invasive carcinoma with lobular features
OBX|159|TX|    Histologic Grade (Nottingham
OBX|160|TX|    Histologic Score)
OBX|161|TX|      Glandular (Acinar) / Tubular
OBX|162|TX|      Differentiation:                 Score 2
OBX|163|TX|      Nuclear Pleomorphism:            Score 2
OBX|164|TX|      Mitotic Rate:                    Score 3
OBX|165|TX|      Overall Nottingham Score:        Grade 2
OBX|166|TX|    Tumour Size:                       Microinvasion only (<= 1  mm)
OBX|167|TX|    Tumour Focality:                   Single focus of invasive carcinoma
OBX|168|TX|    Lymphovascular Invasion:           Present
OBX|169|TX|  In Situ Component:                   Not identified
OBX|170|TX| 
OBX|171|TX|MARGINS
OBX|172|TX|  Invasive Carcinoma Margins:          Cannot be assessed
OBX|173|TX|  DCIS Margins:                        No DCIS present in specimen
OBX|174|TX| 
OBX|175|TX|LYMPH NODES, REGIONAL
OBX|176|TX|                                       No lymph nodes present
OBX|177|TX| 
OBX|178|TX|TREATMENT EFFECT
OBX|179|TX|                                       Presurgical therapy
OBX|180|TX|  In the Breast:                       No residual invasive carcinoma is present in
OBX|181|TX|                                       the breast after presurgical therapy
OBX|182|TX| 
OBX|183|TX|PATHOLOGIC STAGE
OBX|184|TX|                                       pT1mi pNX
OBX|185|TX| 
OBX|186|TX|ANCILLARY STUDIES
OBX|187|TX|  Best Tumour Block(s):                test
OBX|188|TX|  Biomarker Testing/Results:           Not performed: test
OBX|189|TX| 
OBX|190|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|191|TX|---------- End of Synoptic Report ----------
OBX|192|TX|--------  Breast DCIS, 5  --------
OBX|193|TX| 
OBX|194|TX|SPECIMEN COMMENT
OBX|195|TX|  Pertains To:                         testing v.7.0.0.13
OBX|196|TX| 
OBX|197|TX|SPECIMEN
OBX|198|TX|  Procedure:                           Excision (less than total mastectomy)
OBX|199|TX|  Specimen Laterality:                 Right
OBX|200|TX| 
OBX|201|TX|TUMOUR
OBX|202|TX|  Estimated Size (extent) of DCIS:     test
OBX|203|TX|  Histologic Type:                     Ductal carcinoma in situ
OBX|204|TX|  Nuclear Grade:                       Grade I (low)
OBX|205|TX|  Necrosis:                            Present, focal (small foci or single cell
OBX|206|TX|                                       necrosis)
OBX|207|TX| 
OBX|208|TX|MARGINS
OBX|209|TX|                                       Cannot be assessed - test
OBX|210|TX| 
OBX|211|TX|LYMPH NODES, REGIONAL
OBX|212|TX|                                       No lymph nodes present
OBX|213|TX| 
OBX|214|TX|PATHOLOGIC STAGE
OBX|215|TX|                                       pTis (DCIS) pN0
OBX|216|TX| 
OBX|217|TX|ANCILLARY STUDIES
OBX|218|TX|  Best Tumour Block(s):                testing
OBX|219|TX|  Biomarker Testing/Results:           Submitted, see separate report: test
OBX|220|TX| 
OBX|221|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|222|TX|---------- End of Synoptic Report ----------
OBX|223|TX|--------  Endometrium - Hysterectomy, 6  --------
OBX|224|TX| 
OBX|225|TX|SPECIMEN COMMENT
OBX|226|TX|  Pertains To:                         testing v.7.0.0.14
OBX|227|TX| 
OBX|228|TX|SPECIMEN
OBX|229|TX|  Procedure:                           Radical hysterectomy
OBX|230|TX| 
OBX|231|TX|TUMOUR
OBX|232|TX|  Histologic Type:                     Endometrioid carcinoma, NOS
OBX|233|TX|  Histologic Grade:                    FIGO grade 2
OBX|234|TX|  Tumour Size:                         3 Centimeters (cm)
OBX|235|TX|  Myometrial Invasion:                 Not identified
OBX|236|TX|  Cervical Stromal Invasion:           Present
OBX|237|TX|  Other Tissue Involvement / Organ
OBX|238|TX|  Involvement:                         Left ovary
OBX|239|TX|  Lymph Vascular Invasion:             Focal (2 or fewer)
OBX|240|TX| 
OBX|241|TX|MARGINS
OBX|242|TX|  Parametrial / Paracervical Margin:   Positive for carcinoma
OBX|243|TX| 
OBX|244|TX|LYMPH NODES, REGIONAL
OBX|245|TX|                                       No lymph nodes present
OBX|246|TX| 
OBX|247|TX|PATHOLOGIC STAGE
OBX|248|TX|                                       pT3a pNX pM1
OBX|249|TX|  pM Site(s):                          Lung
OBX|250|TX| 
OBX|251|TX|ANCILLARY STUDIES
OBX|252|TX|  Best Tumour Block(s):                testing
OBX|253|TX|  Biomarker Testing:                   Performed previously: test
OBX|254|TX| 
OBX|255|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|256|TX|---------- End of Synoptic Report ----------
OBX|257|TX|--------  GIST - Biopsy, 7  --------
OBX|258|TX| 
OBX|259|TX|SPECIMEN COMMENT
OBX|260|TX|  Pertains To:                         testing v.7.0.0.7
OBX|261|TX| 
OBX|262|TX|SPECIMEN
OBX|263|TX|  Procedure:                           Endoscopic biopsy
OBX|264|TX| 
OBX|265|TX|TUMOUR
OBX|266|TX|  Tumour Site:                         Small Intestine
OBX|267|TX|  Histologic Type:                     GIST, epithelioid type
OBX|268|TX|  Histologic Grade:                    G2: High grade; mitotic rate > 5 / 5 mm2
OBX|269|TX|  Risk Assessment:                     High risk
OBX|270|TX| 
OBX|271|TX|TREATMENT EFFECT
OBX|272|TX|                                       Present
OBX|273|TX| 
OBX|274|TX|ANCILLARY STUDIES
OBX|275|TX|  Best Tumour Block(s):                test
OBX|276|TX|  Biomarker Testing / Results:         Performed, addendum to follow: test
OBX|277|TX| 
OBX|278|TX| 
OBX|279|TX| 
OBX|280|TX|                                       Risk Assessment reference: 1 Miettinen M,
OBX|281|TX|                                       Lasota J. Gastrointestinal stromal tumors:
OBX|282|TX|                                       pathology and prognosis at different sites.
OBX|283|TX|                                       Semin Diagn Pathol. 2006;23(2):70-83.
OBX|284|TX| 
OBX|285|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|286|TX|---------- End of Synoptic Report ----------
OBX|287|TX|--------  Lung - Resection, 8  --------
OBX|288|TX| 
OBX|289|TX|SPECIMEN COMMENT
OBX|290|TX|  Pertains To:                         testing v.7.0.0.13
OBX|291|TX| 
OBX|292|TX|SPECIMEN
OBX|293|TX|  Procedure:                           Wedge resection
OBX|294|TX|  Specimen Laterality:                 Left
OBX|295|TX| 
OBX|296|TX|TUMOUR
OBX|297|TX|  Tumour Site:                         Lower lobe
OBX|298|TX|  Tumour Focality:                     Separate tumour nodules of same
OBX|299|TX|                                       histopathologic type (intrapulmonary
OBX|300|TX|                                       metastases) in same lobe
OBX|301|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|302|TX|  Histologic Type:                     Minimally invasive adenocarcinoma,
OBX|303|TX|                                       nonmucinous
OBX|304|TX|  Visceral Pleura Invasion:            Present
OBX|305|TX|  Direct Invasion of Adjacent
OBX|306|TX|  Structures:                          Adjacent structures present but not involved
OBX|307|TX|  Lymphovascular Invasion:             Present
OBX|308|TX| 
OBX|309|TX|MARGINS
OBX|310|TX|                                       All margins are negative for carcinoma
OBX|311|TX|  Margins Examined:                    Bronchial, Vascular, Parenchymal
OBX|312|TX| 
OBX|313|TX|LYMPH NODES, REGIONAL
OBX|314|TX|                                       No lymph nodes present
OBX|315|TX| 
OBX|316|TX|TREATMENT EFFECT
OBX|317|TX|                                       No known presurgical therapy
OBX|318|TX| 
OBX|319|TX|PATHOLOGIC STAGE
OBX|320|TX|                                       pT3 pNX
OBX|321|TX| 
OBX|322|TX|ANCILLARY STUDIES
OBX|323|TX|  Best Tumour Block(s):                test
OBX|324|TX|  Biomarker Testing/Results:           Performed, see separate report: test
OBX|325|TX| 
OBX|326|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|327|TX|---------- End of Synoptic Report ----------
OBX|328|TX|--------  Stomach, 9  --------
OBX|329|TX| 
OBX|330|TX|SPECIMEN COMMENT
OBX|331|TX|  Pertains To:                         testing v.7.0.0.5
OBX|332|TX| 
OBX|333|TX|SPECIMEN
OBX|334|TX|  Procedure:                           Total gastrectomy
OBX|335|TX| 
OBX|336|TX|TUMOUR
OBX|337|TX|  Tumour Site:                         Fundus
OBX|338|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|339|TX|  Histologic Type:                     Large cell neuroendocrine carcinoma
OBX|340|TX|  Histologic Grade:                    G3: Poorly differentiated, undifferentiated
OBX|341|TX|  Tumour Extension:                    Tumour invades the submucosa
OBX|342|TX|  Lymphovascular Invasion:             Present
OBX|343|TX| 
OBX|344|TX|TREATMENT EFFECT
OBX|345|TX|                                       Residual cancer with evident tumour
OBX|346|TX|                                       regression, but more than single cells or
OBX|347|TX|                                       rare small groups of cancer cells (partial
OBX|348|TX|                                       response, score 2)
OBX|349|TX| 
OBX|350|TX|MARGINS
OBX|351|TX|  Proximal Margin:                     Negative for invasive carcinoma
OBX|352|TX|    Status of Dysplasia at Proximal    Positive for carcinoma in situ (high-grade
OBX|353|TX|    Margin:                            dysplasia)
OBX|354|TX|  Distal Margin:                       Negative for invasive carcinoma
OBX|355|TX|    Status of Dysplasia at Distal      Positive for carcinoma in situ (high-grade
OBX|356|TX|    Margin:                            dysplasia)
OBX|357|TX|  Omental (Radial) Margins:            Negative for invasive carcinoma
OBX|358|TX| 
OBX|359|TX|LYMPH NODES, REGIONAL
OBX|360|TX|                                       No lymph nodes present
OBX|361|TX| 
OBX|362|TX|PATHOLOGIC STAGE
OBX|363|TX|                                       pT1b pNX
OBX|364|TX| 
OBX|365|TX|ANCILLARY STUDIES
OBX|366|TX|  Best Tumour Block(s):                test
OBX|367|TX|  Biomarker Testing/Results:           Not performed: test
OBX|368|TX| 
OBX|369|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|370|TX|---------- End of Synoptic Report ----------
OBX|371|TX|--------  Ureter Renal Pelvis - Biopsy, 10  --------
OBX|372|TX| 
OBX|373|TX|SPECIMEN
OBX|374|TX|  Specimen:                            Renal pelvis
OBX|375|TX|  Specimen Laterality:                 Right
OBX|376|TX| 
OBX|377|TX|TUMOUR
OBX|378|TX|  Tumour Configuration:                Flat
OBX|379|TX|  Histologic Type:                     Urothelial carcinoma, invasive
OBX|380|TX|  Histologic Grade:                    High-grade
OBX|381|TX|  Tumour Extension:                    Tumour invades the muscularis
OBX|382|TX| 
OBX|383|TX|ANCILLARY STUDIES
OBX|384|TX|  Best Tumour Block(s):                test
OBX|385|TX|  Biomarker Testing/Results:           Performed previously: test
OBX|386|TX| 
OBX|387|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|388|TX|---------- End of Synoptic Report ----------
OBX|389|TX|--------  Colon and Rectum - Resection, 11  --------
OBX|390|TX| 
OBX|391|TX|SPECIMEN COMMENT
OBX|392|TX|  Pertains To:                         testing v.7.0.0.20
OBX|393|TX| 
OBX|394|TX|SPECIMEN
OBX|395|TX|  Procedure:                           Right hemicolectomy
OBX|396|TX|  Macroscopic Tumour Perforation:      Present
OBX|397|TX| 
OBX|398|TX|TUMOUR
OBX|399|TX|  Tumour Site:                         Cecum
OBX|400|TX|  Histologic Type:                     Adenocarcinoma
OBX|401|TX|  Histologic Grade:                    G1: Well differentiated (Low grade)
OBX|402|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|403|TX|  Tumour Extension:                    Tumour invades through the muscularis
OBX|404|TX|                                       propria into pericolorectal tissue
OBX|405|TX|  Lymphovascular Invasion:             Present
OBX|406|TX|  Perineural Invasion:                 Present
OBX|407|TX| 
OBX|408|TX|MARGINS
OBX|409|TX|  Proximal Margin:                     Cannot be assessed
OBX|410|TX|  Distal Margin:                       Cannot be assessed
OBX|411|TX|  Radial or Mesenteric Margin:         Not applicable
OBX|412|TX| 
OBX|413|TX|LYMPH NODES, REGIONAL
OBX|414|TX|                                       No lymph nodes present
OBX|415|TX| 
OBX|416|TX|TREATMENT EFFECT
OBX|417|TX|                                       Single cells or rare small groups of cancer
OBX|418|TX|                                       cells (near complete response, score 1)
OBX|419|TX| 
OBX|420|TX|PATHOLOGIC STAGE
OBX|421|TX|                                       pT3 pNX
OBX|422|TX| 
OBX|423|TX|ANCILLARY STUDIES
OBX|424|TX|  Best Tumour Block(s):                test
OBX|425|TX|  Biomarker Testing:                   Not performed: test
OBX|426|TX| 
OBX|427|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|428|TX|---------- End of Synoptic Report ----------
OBX|429|TX|--------  GIST - Resection, 12  --------
OBX|430|TX| 
OBX|431|TX|SPECIMEN COMMENT
OBX|432|TX|  Pertains To:                         Testing v.7.0.0.5
OBX|433|TX| 
OBX|434|TX|SPECIMEN
OBX|435|TX|  Procedure:                           Resection
OBX|436|TX|    Type:                              test
OBX|437|TX| 
OBX|438|TX|TUMOUR
OBX|439|TX|  Tumour Site:                         Colon
OBX|440|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|441|TX|  Tumour Focality:                     Unifocal
OBX|442|TX|  Histologic Type:                     GIST, spindle cell type
OBX|443|TX|  Histologic Grade:                    G2: High grade; mitotic rate > 5 / 5 mm2
OBX|444|TX|  Mitotic Rate:                        4 mitoses per 5 mm2
OBX|445|TX|  Risk Assessment:                     Low risk
OBX|446|TX| 
OBX|447|TX|MARGINS
OBX|448|TX|                                       Negative for GIST
OBX|449|TX|  Distance of Tumour from Closest
OBX|450|TX|  Margin:                              3 Millimeters (mm)
OBX|451|TX| 
OBX|452|TX|LYMPH NODES, REGIONAL
OBX|453|TX|                                       No lymph nodes present
OBX|454|TX| 
OBX|455|TX|TREATMENT EFFECT
OBX|456|TX|  Preresection Treatment:              Systemic therapy performed - test
OBX|457|TX|  Treatment Effect:                    Present
OBX|458|TX| 
OBX|459|TX|PATHOLOGIC STAGE
OBX|460|TX|                                       pT2 pN0
OBX|461|TX| 
OBX|462|TX|ANCILLARY STUDIES
OBX|463|TX|  Best Tumour Block(s):                test
OBX|464|TX|  Biomarker Testing / Results:         Performed, see separate report: test
OBX|465|TX| 
OBX|466|TX| 
OBX|467|TX| 
OBX|468|TX|                                       Risk Assessment reference: 1 Miettinen M,
OBX|469|TX|                                       Lasota J. Gastrointestinal stromal tumors:
OBX|470|TX|                                       pathology and prognosis at different sites.
OBX|471|TX|                                       Semin Diagn Pathol. 2006;23(2):70-83.
OBX|472|TX| 
OBX|473|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|474|TX|---------- End of Synoptic Report ----------
OBX|475|TX|--------  Ureter Renal Pelvis - Biopsy, 13  --------
OBX|476|TX| 
OBX|477|TX|SPECIMEN COMMENT
OBX|478|TX|  Pertains To:                         testing v.7.0.0.4
OBX|479|TX| 
OBX|480|TX|SPECIMEN
OBX|481|TX|  Specimen:                            Ureter
OBX|482|TX| 
OBX|483|TX|TUMOUR
OBX|484|TX|  Tumour Configuration:                Papillary
OBX|485|TX|  Histologic Type:                     Urothelial carcinoma, invasive
OBX|486|TX|  Histologic Grade:                    High-grade
OBX|487|TX|  Tumour Extension:                    Tumour invades subepithelial connective
OBX|488|TX|                                       tissue
OBX|489|TX| 
OBX|490|TX|ANCILLARY STUDIES
OBX|491|TX|  Best Tumour Block(s):                test
OBX|492|TX|  Biomarker Testing/Results:           Performed, see separate report: test
OBX|493|TX| 
OBX|494|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|495|TX|---------- End of Synoptic Report ----------
OBX|496|TX|--------  Colon and Rectum Excisional Biopsy (Polypectomy), 14  --------
OBX|497|TX| 
OBX|498|TX|SPECIMEN COMMENT
OBX|499|TX|  Pertains To:                         testing
OBX|500|TX| 
OBX|501|TX|TUMOUR
OBX|502|TX|  Tumour Site:                         Cecum
OBX|503|TX|  Histologic Type:                     Adenocarcinoma
OBX|504|TX|  Histologic Grade:                    G1: Well differentiated (Low grade)
OBX|505|TX|  Tumour Extension:                    Tumour invades submucosa
OBX|506|TX|  Lymphovascular Invasion:             Present
OBX|507|TX| 
OBX|508|TX|MARGINS
OBX|509|TX|  Deep Margin:                         Negative for invasive carcinoma
OBX|510|TX|    Distance of Invasive Carcinoma
OBX|511|TX|    from Margin:                       4 Millimeters (mm)
OBX|512|TX|  Mucosal Margin:                      Negative for invasive carcinoma
OBX|513|TX| 
OBX|514|TX|PATHOLOGIC STAGE
OBX|515|TX|                                       pT1
OBX|516|TX| 
OBX|517|TX|ANCILLARY STUDIES
OBX|518|TX|  Best Tumour Block(s):                test
OBX|519|TX|  Biomarker Testing:                   Not performed: test
OBX|520|TX| 
OBX|521|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC June 2017
OBX|522|TX|---------- End of Synoptic Report ----------
OBX|523|TX|--------  Adrenal - Biopsy; Resection, 15  --------
OBX|524|TX| 
OBX|525|TX|SPECIMEN COMMENT
OBX|526|TX|  Pertains To:                         testing v.7.0.0.6
OBX|527|TX| 
OBX|528|TX|SPECIMEN
OBX|529|TX|  Procedure:                           Adrenalectomy, total
OBX|530|TX|  Specimen Laterality:                 Bilateral
OBX|531|TX| 
OBX|532|TX|TUMOUR
OBX|533|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|534|TX|  Weight:                              3 g
OBX|535|TX|  Histologic Type:                     Adrenal cortical carcinoma, oncocytic type
OBX|536|TX|  Histologic Grade:                    High grade
OBX|537|TX|  Tumour Extension:                    Tumour invades into or through the adrenal
OBX|538|TX|                                       capsule
OBX|539|TX|  Lymphovascular Invasion:             Large vessel invasion, not otherwise
OBX|540|TX|                                       specified;  Microscopic angioinvasion
OBX|541|TX|  Tumour Description:                  Necrotic
OBX|542|TX| 
OBX|543|TX|MARGINS
OBX|544|TX|                                       Negative for tumour
OBX|545|TX|  Margin:                              test
OBX|546|TX| 
OBX|547|TX|LYMPH NODES, REGIONAL
OBX|548|TX|                                       No lymph nodes present
OBX|549|TX| 
OBX|550|TX|PATHOLOGIC STAGE
OBX|551|TX|                                       mpT1 pNX
OBX|552|TX| 
OBX|553|TX|ANCILLARY STUDIES
OBX|554|TX|  Best Tumour Block(s):                test
OBX|555|TX|  Ancillary Studies:                   Ki-67 labeling index - 4%, Reticulin stain -
OBX|556|TX|                                       test, test
OBX|557|TX| 
OBX|558|TX|COMMENTS
OBX|559|TX|                                       test
OBX|560|TX| 
OBX|561|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC  February 2019
OBX|562|TX|---------- End of Synoptic Report ----------
OBX|563|TX|--------  Prostate - Needle Biopsy Summary, 16  --------
OBX|564|TX| 
OBX|565|TX|SPECIMEN COMMENT
OBX|566|TX|  Pertains To:                         testing v.2.0.0.27
OBX|567|TX| 
OBX|568|TX|TUMOUR
OBX|569|TX|  Histologic Type:                     Adenocarcinoma (acinar)
OBX|570|TX|  Histologic Grade
OBX|571|TX|    Grade Group and Gleason Score:     Grade group 3 (Gleason Score 4 + 3 = 7)
OBX|572|TX|      Percentage of Pattern 4:         60%
OBX|573|TX|  Lymph-Vascular Invasion:             Present
OBX|574|TX|  Total Number of Cores:               6
OBX|575|TX|  Number of Positive Cores:            1
OBX|576|TX|  Number of Cores Positive on Left
OBX|577|TX|  Side:                                1
OBX|578|TX|  Number of Cores Positive on Right
OBX|579|TX|  Side:                                0
OBX|580|TX|  Total Linear Span of Carcinoma in
OBX|581|TX|  Cores:                               5 mm
OBX|582|TX|  Total Length of Positive Needle
OBX|583|TX|  Cores:                               10 mm
OBX|584|TX|  Proportion of Positive Cores
OBX|585|TX|  Involved by Tumour:                  50 %
OBX|586|TX|  Periprostatic Fat Invasion:          Present
OBX|587|TX|  Seminal Vesicle Invasion:            Present
OBX|588|TX| 
OBX|589|TX|Based on AJCC/UICC TNM, 7th edition
OBX|590|TX|---------- End of Synoptic Report ----------
OBX|591|TX|--------  Prostate - Radical Prostatectomy, 17  --------
OBX|592|TX| 
OBX|593|TX|SPECIMEN COMMENT
OBX|594|TX|  Pertains To:                         testing v.7.0.0.16
OBX|595|TX| 
OBX|596|TX|SPECIMEN
OBX|597|TX|  Procedure:                           Radical prostatectomy
OBX|598|TX| 
OBX|599|TX|TUMOUR
OBX|600|TX|  Histologic Type:                     Acinar adenocarcinoma
OBX|601|TX|  Histologic Grade
OBX|602|TX|    Grade Group and Gleason Score:     Grade group 5 (Gleason Score 5 + 4 = 9)
OBX|603|TX|    Tertiary Gleason Pattern:          Grade 3
OBX|604|TX|    Percentage of Pattern 4:           25 %
OBX|605|TX|    Percentage of Pattern 5:           50 %
OBX|606|TX|  Extraprostatic Extension (EPE):      Not identified
OBX|607|TX|  Urinary Bladder Neck Invasion:       Not identified
OBX|608|TX|  Seminal Vesicle Invasion:            Present
OBX|609|TX|  Treatment Effect:                    No known presurgical therapy
OBX|610|TX| 
OBX|611|TX|MARGINS
OBX|612|TX|                                       Negative for invasive carcinoma
OBX|613|TX| 
OBX|614|TX|LYMPH NODES, REGIONAL
OBX|615|TX|                                       No lymph nodes present
OBX|616|TX| 
OBX|617|TX|PATHOLOGIC STAGE
OBX|618|TX|                                       pT3b pNX
OBX|619|TX| 
OBX|620|TX|ANCILLARY STUDIES
OBX|621|TX|  Best Tumour Block(s):                test
OBX|622|TX| 
OBX|623|TX|Based on AJCC/UICC TNM, 8th edition;  CAP eCC June 2017
OBX|624|TX|---------- End of Synoptic Report ----------
OBX|625|TX|--------  Prostate - Radical Prostatectomy, 18  --------
OBX|626|TX| 
OBX|627|TX|SPECIMEN COMMENT
OBX|628|TX|  Pertains To:                         testing v.7.0.0.17
OBX|629|TX| 
OBX|630|TX|SPECIMEN
OBX|631|TX|  Procedure:                           Radical prostatectomy
OBX|632|TX| 
OBX|633|TX|TUMOUR
OBX|634|TX|  Histologic Type:                     Acinar adenocarcinoma
OBX|635|TX|  Histologic Grade
OBX|636|TX|    Grade Group and Gleason Score:     Grade group 4 (Gleason Score 5 + 3 = 8)
OBX|637|TX|    Tertiary Gleason Pattern:          Grade 4
OBX|638|TX|    Percentage of Pattern 4:           25 %
OBX|639|TX|    Percentage of Pattern 5:           50 %
OBX|640|TX|  Extraprostatic Extension (EPE):      Present, focal
OBX|641|TX|  Urinary Bladder Neck Invasion:       Not identified
OBX|642|TX|  Seminal Vesicle Invasion:            Not identified
OBX|643|TX|  Treatment Effect:                    Not identified
OBX|644|TX| 
OBX|645|TX|MARGINS
OBX|646|TX|                                       Negative for invasive carcinoma
OBX|647|TX| 
OBX|648|TX|LYMPH NODES, REGIONAL
OBX|649|TX|                                       No lymph nodes present
OBX|650|TX| 
OBX|651|TX|PATHOLOGIC STAGE
OBX|652|TX|                                       pT3a pNX
OBX|653|TX| 
OBX|654|TX|ANCILLARY STUDIES
OBX|655|TX|  Best Tumour Block(s):                test
OBX|656|TX| 
OBX|657|TX|Based on AJCC/UICC TNM, 8th edition;  CAP eCC February 2019
OBX|658|TX|---------- End of Synoptic Report ----------
OBX|659|TX|--------  Prostate - TUR; Enucleation Specimen, 19  --------
OBX|660|TX| 
OBX|661|TX|SPECIMEN COMMENT
OBX|662|TX|  Pertains To:                         testing v.7.0.0.6
OBX|663|TX| 
OBX|664|TX|SPECIMEN
OBX|665|TX|  Procedure:                           Enucleation
OBX|666|TX| 
OBX|667|TX|TUMOUR
OBX|668|TX|  Histologic Type:                     Ductal adenocarcinoma
OBX|669|TX|  Histologic Grade
OBX|670|TX|    Grade Group and Gleason Score:     Grade group 5 (Gleason Score 5 + 5 = 10)
OBX|671|TX|    Percentage of Pattern 5:           100%
OBX|672|TX|  Estimated Percentage of Prostatic
OBX|673|TX|  Tissue Involved by Tumour:           25%
OBX|674|TX|  Periprostatic Fat Invasion:          Present
OBX|675|TX| 
OBX|676|TX|ANCILLARY STUDIES
OBX|677|TX|  Best Tumour Block(s):                test
OBX|678|TX| 
OBX|679|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|680|TX|---------- End of Synoptic Report ----------
OBX|681|TX|--------  Testis - Orchiectomy, 20  --------
OBX|682|TX| 
OBX|683|TX|SPECIMEN COMMENT
OBX|684|TX|  Pertains To:                         testing v.7.0.0.8
OBX|685|TX| 
OBX|686|TX|SPECIMEN
OBX|687|TX|  Specimen Laterality:                 Not specified
OBX|688|TX| 
OBX|689|TX|TUMOUR
OBX|690|TX|  Histologic Type:                     Sex cord-stromal tumour type, unclassified;
OBX|691|TX|                                       Mixed germ cell-sex cord stromal tumour,
OBX|692|TX|                                       gonadoblastoma
OBX|693|TX|    Histologic Type Comments:          test
OBX|694|TX|  Tumour Focality:                     Unifocal
OBX|695|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|696|TX|  Tumour Extension:                    Tumour invades hilar soft tissue
OBX|697|TX|  Lymphovascular Invasion:             Present
OBX|698|TX| 
OBX|699|TX|MARGINS
OBX|700|TX|  Spermatic Cord Margin:               Negative for tumour
OBX|701|TX|  Other Margin(s):                     Negative for tumour
OBX|702|TX|    Margin(s):                         test
OBX|703|TX| 
OBX|704|TX|LYMPH NODES, REGIONAL
OBX|705|TX|                                       No lymph nodes present
OBX|706|TX| 
OBX|707|TX|PATHOLOGIC STAGE
OBX|708|TX|                                       pT2 pNX
OBX|709|TX| 
OBX|710|TX|ANCILLARY STUDIES
OBX|711|TX|  Best Tumour Block(s):                test
OBX|712|TX| 
OBX|713|TX|ADDITIONAL FINDINGS
OBX|714|TX|                                       Microlith
OBX|715|TX| 
OBX|716|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|717|TX|---------- End of Synoptic Report ----------
OBX|718|TX|--------  Urinary Bladder - Biopsy; TURBT, 21  --------
OBX|719|TX| 
OBX|720|TX|SPECIMEN COMMENT
OBX|721|TX|  Pertains To:                         testing v.7.0.0.4
OBX|722|TX| 
OBX|723|TX|SPECIMEN
OBX|724|TX|  Procedure:                           Transurethral resection of bladder (TURBT)
OBX|725|TX| 
OBX|726|TX|TUMOUR
OBX|727|TX|  Tumour Site:                         Dome
OBX|728|TX|  Histologic Type:                     Urothelial carcinoma, invasive
OBX|729|TX|  Histologic Grade:                    G1: Well differentiated
OBX|730|TX|  Muscularis Propria Presence:         Muscularis propria (detrusor muscle) present
OBX|731|TX|  Tumour Extension:                    Urothelial carcinoma involving prostatic
OBX|732|TX|                                       urethra in prostatic chips sampled by TURBT
OBX|733|TX|  Lymphovascular Invasion:             Present
OBX|734|TX| 
OBX|735|TX|ANCILLARY STUDIES
OBX|736|TX|  Best Tumour Block(s):                test
OBX|737|TX| 
OBX|738|TX|ADDITIONAL PATHOLOGIC FINDINGS
OBX|739|TX|                                       Urothelial dysplasia
OBX|740|TX| 
OBX|741|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|742|TX|---------- End of Synoptic Report ----------
OBX|743|TX|--------  Urinary Bladder - Cystectomy, 22  --------
OBX|744|TX| 
OBX|745|TX|SPECIMEN COMMENT
OBX|746|TX|  Pertains To:                         testing v.7.0.0.7
OBX|747|TX| 
OBX|748|TX|SPECIMEN
OBX|749|TX|  Procedure:                           Radical cystectomy (total cystectomy)
OBX|750|TX| 
OBX|751|TX|TUMOUR
OBX|752|TX|  Tumour Site:                         Dome
OBX|753|TX|  Histologic Type:                     Urothelial carcinoma invasive
OBX|754|TX|  Histologic Grade:                    G2: Moderately differentiated
OBX|755|TX|  Tumour Size:                         4 Centimeters (cm)
OBX|756|TX|  Tumour Extension:                    Tumour invades perivesical tissue
OBX|757|TX|    Extent of Perivesical Invasion:    Microscopically
OBX|758|TX|  Tumour Configuration:                Ulcerated
OBX|759|TX|  Lymphovascular Invasion:             Present
OBX|760|TX| 
OBX|761|TX|MARGINS
OBX|762|TX|                                       Negative for invasive carcinoma and
OBX|763|TX|                                       carcinoma in situ / noninvasive urothelial
OBX|764|TX|                                       carcinoma
OBX|765|TX| 
OBX|766|TX|LYMPH NODES, REGIONAL
OBX|767|TX|                                       No lymph nodes present
OBX|768|TX| 
OBX|769|TX|PATHOLOGIC STAGE
OBX|770|TX|                                       pT3a pNX
OBX|771|TX| 
OBX|772|TX|ANCILLARY TESTING
OBX|773|TX|  Best Tumour Block(s):                test
OBX|774|TX| 
OBX|775|TX|ADDITIONAL PATHOLOGIC FINDINGS
OBX|776|TX|                                       Urothelial dysplasia
OBX|777|TX| 
OBX|778|TX|Based on AJCC/UICC TNM, 8th edition; CAP eCC February 2019
OBX|779|TX|---------- End of Synoptic Report ----------
OBX|780|TX|--------  Breast Biomarkers, 23  --------
OBX|781|TX| 
OBX|782|TX|SPECIMEN
OBX|783|TX|                                       Submitting Hospital Case Number:   ; Block
OBX|784|TX|                                       Tested: test
OBX|785|TX| 
OBX|786|TX|BREAST BIOMARKER TESTS
OBX|787|TX|  Ki-67:                               Low (Less than 10%)
OBX|788|TX| 
OBX|789|TX|---------- End of Synoptic Report ----------
OBX|790|TX| 
OBX|791|TX|SPECIMEN SUBMITTED
OBX|792|TX|TURB
OBX|793|TX|                                                    ____________________________________
OBX|794|TX|                                                    Brigette Rabel
OBX|795|TX|                                                    Electronically signed: 28/Nov/2019
OBX|796|TX| 
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OBX|809|TX| 

